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The ortho-hydroxy metabolite undergoes further metabolism via glucuronidation.
- What should I avoid while taking atorvastatin?
- Also call your doctor at once if you have:
- Take the missed dose as soon as you remember.
- It is also an inhibitor of cytochrome 3A4.
As a substrate for the CYP3A4 isozyme, it has shown susceptibility to inhibitors and inducers of CYP3A4 to produce increased or decreased plasma concentrations, respectively. It is also an inhibitor of camstarmall.com thought to be due to the active metabolites.
Atorvastatin is also a substrate of the intestinal P-glycoprotein efflux transporter, which pumps Atorvastatin medication back into the intestinal lumen during medication absorption.
Additionally, Atorvastatin Australia, healthy elderly people show a greater pharmacodynamic response to atorvastatin at any dose; therefore, this population may Atorvastatin lower effective doses. This phenomenon is suspected to be related to increased plasma levels Atorvastatin pharmacologically active metabolites, such as atorvastatin lactone and p-hydroxyatorvastatin. Australia and its active metabolites may be monitored in potentially susceptible people using specific chromatographic techniques. Mevacor, which was first marketed in 1987, was the industry’s first statin and Merck’s synthetic version — simvastatin — was in the advanced stages of development.
Your blood work will Australia your doctor determine how long to treat you with atorvastatin.
For the Consumer
You may need to take atorvastatin for a long time or for life depending on your medical history. Atorvastatin is only part of a complete treatment program that may also include diet, exercise, and weight control.
Store at room temperature away from moisture, heat, Atorvastatin Australia, and light. Atorvastatin dosage information in more detail What happens if I miss a dose? Take the missed dose as soon as you remember.
Skip the missed dose if your next dose is less than 12 hours away. Do not take extra medicine to make up the missed dose, Atorvastatin Australia. What happens if I overdose? Seek emergency medical attention or call the Poison Help Australia at 1-800-222-1222. What should I avoid while taking Atorvastatin Avoid eating foods that are high in fat or cholesterol.
Atorvastatin will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan. It can raise triglyceride levels and may increase your risk of liver damage. Atorvastatin side effects Get emergency medical help if you have signs of an allergic reaction to atorvastatin: In rare cases, atorvastatin can cause a condition that results in the breakdown of skeletal muscle tissue, potentially leading to kidney failure.
Call your doctor right away if you have unexplained muscle pain, Atorvastatin, or weakness especially if you also have fever, Atorvastatin Australia, unusual tiredness, and dark colored urine. Also Australia your doctor at once if you have: